东港安泰医院 黄渼媄药师

◎Special consideration

*25%以上的病患会?发pseudocystes(假孕)intestinal & pancreatic fistula(?管)

*Pancreatic abscess(脓疡)及pancreatic ascites(腹水),这些并发症会使EN进行困难。当病患有这些并发症时需考虑使用PN。AP病患可否使用lipid emmulsions?

*大部分病患可耐受glucose及lipid based formulas,但血中TG浓度>400mg/dl时需hold。无脂肪输液之PN不建议使用>两周以上,易造成必须脂肪酸之缺乏。

◎Drug Point System

* Pancreatin---DONNAZYME
* Dosage of Adult
* Pancreatic insufficiency:2 tablet(1000mg) orally with each meal and 2 tablets
* taken with food eaten between meals
* Pancrelipase---
* Dosage of Adult
* 8000-32000 lipase USP units Orally taken per Meal or snack(点 心)。

◎Treatment
急性胰脏炎--- Supportive treatment
* Narcotic analgesics usually are necessary for pain relief.最常使用Meperidine because it has no significant effect on the sphincter of Oddi。病患需禁食,直到不再疼痛和nausea。H2-recepter antagonist may be needed in severely ill patients with significant risk factors for stress ulcer bleeding。

◎Treatment
慢性胰脏炎---严重的剧痛,通常需要用到Narcotics,但是也有成瘾性的问题。
* 口服补充pancreatic enzyme 可能有益于控制疼痛。
* 病患有intractable(难治愈的) pain 可考虑外科手术处理。

◎参考文献
The Washington Manual Of Medical Therapeutics 29th Edition
* MICROMEDEX(R) Healthcare Series Vol.
* A.S.P.E.N. BOARD OF DIRECTORS

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